LU Yi

LU Yi

PhD, Principal investigator
Director of the Shenzhen Engineering Lab for Brain Activity Mapping Technologies (BAMT)
Office Phone: 
0755-86132705
Email: 
Lab Website: 

Research

(1) Novel research tools and techniques for neural recording and modulation, including flexible optogenetics, bio-sensors & actuators, electrode/optrode arrays, neural interfaces.
(2) Functional dissection and modulation of specific neural circuits involved in neuropsychological diseases (epilepsy and emotion disorders).

鲁艺研究员目前担任深圳市脑图谱解析关键技术与设备工程实验室主任;获得“广东省杰出青年”项目资助,入选“中国科学院青年创新促进会”,深圳市高层次人才(地方级)。已在Nature Communications,Biomaterials等期刊上发表学术论文20余篇,担任Advanced Materials, Advanced Science等期刊审稿人。申请国家发明专利70余件(已授权40件)。获得2018年度广东省自然科学一等奖(第二完成人),主持国家自然科学基金委(青年、面上),中国科学院(青年创新促进会),广东省基金委(杰出青年项目),深圳市发改委(工程实验室组建),深圳市科创委(技术攻关、技术开发、基础研究)等项目。

主要的研究方向包括:(1)神经调控和解析技术研发(光遗传学、神经电极技术);(2)病理状态下的神经环路机制研究(癫痫、情绪障碍);(3)神经组织工程(生物材料、神经界面)。实验室已建立完善的跨学科研究平台,现提供研究岗位(博后、研究助理),并常年招收研究生(含客座学生),欢迎对交叉学科研究感兴趣的候选人直接联系(luyi@siat.ac.cn)。




Biography

2018-present, Principal Investigator and Professor at SIAT, CAS.
2014-present, Director of the Shenzhen Engineering Lab for BAMT.
2012-2018, Associate Professor at SIAT, CAS.
2010-2012, Assistant Professor at SIAT, CAS.
2005-2010, Ph.D. in Physical Chemistry, Wuhan University.
2001-2005, B.S. in Chemistry, Wuhan University.

Selected publications

(#Equal contribution; *Corresponding Author)

  1. Chen HX#, Wang LL#, Lu Y*, Du XM*, Bioinspired microcone array-based living biointerfaces: enhancing anti-inflammatory effect and neuronal network formation. Microsystems & Nanoengineering, in press.
  2. Wang LL#, Xie ZX#, Zhong C, Tang YQ, Ye FM, Wang LP*, Lu Y*. Self-spreadable Octopus-like Electrode Arrays for Long-term Neural Recordings. Acta Physico-Chimica Sinica. 2020;36:1909035.
  3. Ye FM#, Li M#, Ke DN, Wang LP, Lu Y*, Ultrafast Self-Healing and Injectable Conductive Hydrogel for Strain and Pressure Sensors. Advanced Materials Technologies, 2019;1900346.
  4. Wang LL#, Zhong C#, Ke DN, Ye FM, Tu J, Wang LP*, Lu Y*, Ultra-soft and Highly Stretchable Hydrogel Optical Fibers for In Vivo Optogenetic Modulations. Advanced Optical Materials, 2018;6:1800427.
  5. Wang LL#, Huang K#, Zhong C, Wang LP*, Lu Y*, Fabrication and modification of implantable optrode arrays for in vivo optogenetic applications. Biophysics Reports, 2018;4:82-93. (Cover Story)
  6. Zhong C, Ke DN, Wang LL, Lu Y*, Wang LP*, Bioactive interpenetrating polymer networks for improving the electrode/neural-tissue interface. Electrochemistry Communications, 2017;79:59-62.
  7. Lu Y#, Zhong C#, Wang LL, Wei PF, He W, Huang K, Zhang Y, Zhan Y, Feng GP, Wang LP*, Optogenetic dissection of ictal propagation in the hippocampal-entorhinal cortex structures, Nature Communications, 2016;7:10962.
  8. Zhong C#, Zhang YY#, He W, Wei PF, Lu Y*, Zhu Y, Liu L, Wang LP*. Multi-unit recording with iridium oxide modified stereotrodes in Drosophila melanogaster, Journal of Neuroscience Methods, 2014;222:218-29.
  9. Lu Y, Li YL, Pan JQ, Wei PF, Liu N, Wu BF, Cheng JB, Lu CY, Wang LP*. Poly(3,4-ethylenedioxythiophene)/poly(styrenesulfonate)-poly(vinyl alcohol)/poly (acrylic acid) interpenetrating polymer networks for improving optrode-neural tissue interface in optogenetics. Biomaterials, 2012;33:378-94.
  10. Lu Y#, Li T#, Zhao XQ, Li M, Cao YL, Yang HX, Duan YY*. Electrodeposited polypyrrole/carbon nanotubes composite films electrodes for neural interfaces. Biomaterials, 2010;31:5169-81.
  11. Lu Y, Wang DF, Li T, Zhao XQ, Cao YL, Yang HX, Duan YY*. Poly(vinyl alcohol)/poly(acrylic acid) hydrogel coatings for improving electrode-neural tissue interface. Biomaterials, 2009;30:4143-51.
  12. Lu Y, Wang TY, Cai ZX, Cao YL, Yang HX, Duan YY*. Anodically electrodeposited iridium oxide films microelectrodes for neural microstimulation and recording. Sensors & Actuators B:Chemical, 2009;137:334-9.
  13. Lu Y, Cai ZX, Cao YL, Yang HX, Duan YY*. Activated iridium oxide films fabricated by asymmetric pulses for electrical neural micro stimulation and recording. Electrochemistry Communications, 2008;10:778-82.