Dr. Qu received her Ph.D. from the University of Bonn, Germany, in 2015. She joined the Institute of Brain Cognition and Brain Disease, Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences，in the same year and is currently an Associate Professor. 
Her research fouceses on elucidating the early pathogenic events in Alzheimer’s disease, particularly the neuroimmune and epigenetic mechanisms that mediate peripheral-central nervous system crosstalk. Through a brain-body interaction framework, she seeks to translate mechanistic insights into early diagnostic tools and targeted immunomodulatory interventions.

Deciphering early epigenetic and neuroimmune drivers of AD.
Developing early biomarkers and therapies from mechanistic insight.

1. Xueqi Qu, Li Lin, Yinhu Li, Yuewen Chen, Yu Chen*. (2025) N6-methyladenosine RNA modification regulates microglial phagocytosis in the APP/PS1 mouse model of Alzheimer's disease. Genes & Immunity, https://doi.org/10.1038/s41435-025-00347-1.  
2. Xueqi Qu, Li Lin, Wangying Yi, Changyu Sun, Yuewen Chen, Yu Chen*. (2022) Early Changes in Transcriptomic Profiles in Synaptodendrosomes Reveal Aberrant Synaptic Functions in Alzheimer's Disease. International Journal of Molecular Sciences, 23(16): 8888.
3. Xueqi Qu*, Christiane Neuhoff*, Mehmet Ulas Cinar, Maren Pröll, Ernst Tholen, Dawit Tesfaye, Michael Hölker, Karl Schellander, Muhammad Jasim Uddin. (2021) Epigenetic Modulation of TLR4 Expression by Sulforaphane Increases Anti-Inflammatory Capacity in Porcine Monocyte-Derived Dendritic Cells. Biology, 10(6): 490.
4. Xueqi Qu, Maren Pröll, Christiane Neuhoff, Rui Zhang, Mehmet Ulas Cinar, Md. Munir Hossain, Dawit Tesfaye, Christine Große-Brinkhaus, Dessie Salilew-Wondim, Ernst Tholen, Christian Looft, Michael Hölker, Karl Schellander, Muhammad Jasim Uddin*. (2015) Sulforaphane epigenetically regulates innate immune responses of porcine monocyte-derived dendritic cells induced with lipopolysaccharide. PLoS One, 10(3): e0121574.
5. Xueqi Qu, Mehmet U Cinar, Huitao Fan, Maren Pröll, Dawit Tesfaye, Ernst Tholen, Christian Looft, Michael Hölker, Karl Schellander, Muhammad J Uddin*. (2014) Comparison of the innate immune responses of porcine monocyte-derived dendritic cells and splenic dendritic cells stimulated with LPS. Innate Immunity, 21(3): 242-254.

Dr. Xueqi Qu has led and participated in Alzheimer's disease research, with total funding exceeding 15 million RMB, focusing on early-stage mechanisms, peripheral–central immune regulation, and biomarker-based interventions. She has led 4 Shenzhen key and innovative projects and contributed to 6 national and provincial projects, establishing a mechanism–intervention–translation research loop that underpins sustained team research and translational outcomes.