Peihua CHEN
Peihua CHEN
个人简介

She obtained Ph.D. in Biomedical Engineering from Zhejiang University in 2010. Her research focuses on neuroscience electrophysiology, synaptic information transmission, and biosensors, with a specialization in designing and fabricating novel sensors for detecting neurotransmitter release.
In 2010, she joined the Institute of Biophysics, Chinese Academy of Sciences, as a postdoctoral researcher, where she established a high-precision synaptic signal detection system.Four invention patents have been granted based on this system, which achieves a technical breakthrough enabling the detection of single synaptic vesicle fusion and quantal neurotransmitter release in the central nervous system.
In 2019, she joined the Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences.

研究领域

Her current research focuses on:

  1. The molecular biological mechanisms of synaptic vesicle exocytosis;
  2. The development of high-precision in vivo detection technologies and instruments for quantal neurotransmitter release from synaptic vesicles.
代表论著

(1) Measurement of intact quantal packet of transmitters released from single nerve terminal by loose-patch amperometry, BIOSENSORS & BIOELECTRONICS, 2021, 第 11 作者

(2) Intestinal microbiota modulates adrenomedullary response through Nod1 sensing in chromaffin cells, ISCIENCE, 2021, 第 2 作者

(3) Loss of Dysbindin Implicates Synaptic Vesicle Replenishment Dysregulation as a Potential Pathogenic Mechanism in Schizophrenia, NEUROSCIENCE, 2021, 第 11 作者

(4) Non-enzymatic fructose sensing by platinum decorated graphene oxide nanocomposite, JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 2019, 第 11 作者

(5) A biomimetic bioelectronic tongue: A switch for On- and Off- response of acid sensations, BIOSENSORS & BIOELECTRONICS, 2017, 第 11 作者

科研\学术成果

已在Journal of Neurosciences, Biosensors and Bioelectronics, Sensors and Actuators, B Chemical等杂志发表15篇学术论文,包括:SCI收录12篇;参与3部专著编写工作,包括1部英文专著和2部中文专著。