个人简介
Yuewen Chen, Associate Investigator, Principal Investigator / PhD Supervisor. Yuewen Chen received his B.Sc. from Lanzhou University in 2005, his M.Sc. from Peking Union Medical College in 2009, and his Ph.D. from Jinan University in 2012 (joint Ph.D. program with The Hong Kong University of Science and Technology).
研究领域
His research focuses on the molecular and cellular mechanisms of cerebral cortex development, as well as diagnostic and therapeutic strategies for developmental brain disorders.
代表论著
1. Hongjiao Wu, Yujie Yang, Wanying Yi, Yue Qiu, Shuangshuang Ma, Jinying Xu, Yingying Fan, Yuewen Chen*, Yu Chen*. Coronin 2B deficiency induces nucleolar stress and neuronal apoptosis. Cell Death & Disease, 15(6):457, 2024
2. Lei Chen, Yang Du, Yang Hu, Xue-Song Li, Yuewen Chen*, Yong Cheng* Whole-exome sequencing of individuals from an isolated population under extreme conditions implicates rare risk variants of schizophrenia. Translational Psychiatry, 14(1):290, 2024
3. Yuewen Chen#, Zhenyan Xu#, Jing Chen#, Yue Qiu, Lin Yuan, Peng Liu, Jing Duan, Li Chen*, Yu Chen*.Coronin 2B Regulates neuronal migration via Rac1-dependent multipolar–bipolar transition. Journal of Neuroscience 43 (2): 211-220, 2023
4. Yuewen Chen#, Jinying Xu#, Yulin Zhang, Shuangshuang Ma, Wanying Yi, Saijuan Liu, Xiaojun Yu, Jiali Wang, Yu Chen. Coronin 2B regulates dendrite outgrowth by modulating actin dynamics. FEBS Letters, 594(18):2975-2987, 2020
5. Yuewen Chen, Fanny C.F. Ip, Lei Shi, Zhe Zhang, Huibin Tang, Yu Pong Ng, Wen-Cai Ye, Amy K.Y. Fu, Nancy Y. Ip, Coronin 6 regulates acetylcholine receptor clustering through modulating receptor anchorage to actin cytoskeleton, Journal of Neuroscience. 34(7):2413-2421, 2014
科研\学术成果
He has published nearly 40 SCI papers in total. He serves as Principal Investigator for the Young Scientists Fund of the National Natural Science Foundation of China and the General Program of the Natural Science Foundation of Guangdong Province.As a core member, he has participated in multiple national, provincial and ministerial research programs, including the National Key R&D Program of China, the NSFC–Hong Kong RGC Joint Research Scheme, the Guangdong Key Fields R&D Program, and the Guangdong–Shenzhen Joint Fund Team Project.