Ke Xiao is an Associate Researcher at the Institute of Brain Research, Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences, a Shenzhen High‑Level Talent, and a core permanent researcher in the Key Laboratory of Research and Evaluation for Viral Vectors of Cell and Gene Therapy Products, National Medical Products Administration. She earned her Ph.D. from Huazhong Agricultural University in 2016 and conducted postdoctoral research at the State Key Laboratory of Agricultural Microbiology, where she was awarded Excellent Postdoctoral Fellow for three consecutive years.She is also a recipient of the Pengcheng Peacock Plan Distinguished Appointment, Shenzhen.

Her long-term research interests include:
Systems biology of the neuro-immune-infection axis: Pathogenesis of inflammatory depression
Interplay between psychiatric disorders and autoimmune diseases
Epigenomic multi-omics studies of inflammatory depression

1. Jinsong Yu#, Ke Xiao#, Lulu Deng, Yue Li, Anran Gao, Chengchao Wu, Lu Zhang, Qiudi Zhou, Junjun Gao, Jiaji Jiao, Sheng Cheng, Zhiqing Guo, Xinmei Yang, Weize Xu, Zheng Guo, Jinxia Dai, Ji Hu, Zhenfang Fu, Gang Cao*. Neuron-derived neuropeptide Y finetunes the splenic immune responses. Neuron, (2022) 110 (8). (Highlighted by Nat. Rev. Neurosci. & Neuron)

2. Ke Xiao#, Dan Xiong#, Gong Chen, Jinsong Yu, Yue Li, Kening Chen, Lu Zhang, Yangyang Xu, Qian Xu, Xi Huang, Anran Gao, Keji Yan, Jinxia Dai, Xueying Hu, Yijun Ruan, Zhenfang Fu*, Guoliang Li*, Gang Cao*. RUNX1-mediated alphaherpesvirus-host trans-species chromatin interaction promotes viral transcription. Science Advances, (2021) 7: eabf8962.

3. Zhe-wei Zhang#, Ke Xiao#, Sheng Wang, Abdur Rahman Ansari, Xiaoyu Niu, Wenjie Yang, Mengqi Lu, Weicheng Bei and Hui Song*. Visfatin is a multifaceted molecule that exerts regulation effects on inflammation and apoptosis in RAW264.7 cells and mice immune organs. Frontiers in Immunology, 2022.

4. Yi Zhang1,2#; Bei Chen1,2#; Yaqin Wang1,2#; Cong Liu1,2; Jiayi Sun1,2; Zhimo Zhang1,2; Liangzi Guan1,2; Ke Xiao3,4,5*; Zhonghai Zhu6*; Jin Luo1,2*. Association between mental health and male fertility: depression, rather than anxiety, is linked to decreased semen quality. Frontiers in Endocrinology, (2024) 15-2024.

5. Danmei Xiao, Yu He, Qin Xiao, Luxia Cai, Haoqi Wang, Aikebaier·Reheman* and Ke Xiao*. The Activity of Plant-Derived Ren’s Oligopeptides-1 against the Pseudorabies Virus. Animals, 2022, 12(11): 1341.

She has been the principal investigator of 1 General Program and 1 Young Scientist Fund from the National Natural Science Foundation of China, 1 Shenzhen Medical Research Special Fund, 2 China Postdoctoral General Programs, and 1 Postdoctoral Research Grant for Shenzhen Retention.As a core member, she has participated in 1 Shenzhen Major Science and Technology Program for Brain Research and 2 National Key R&D Programs of the 13th and 14th Five-Year Plan periods, with a total awarded funding of 4 million yuan. Her research has received extensive attention from top journals and media.It has been highlighted in leading international journals including Nature Genetics, Nature Reviews Neuroscience, and Neuron, and has also been widely covered by outlets such as the International Innovation Center of Science and Technology and ScienceNet.cn.