Professor Pak-Ming Lau received hers B.S. in Physics from Peking University and hers Ph.D. in Molecular and Cell Biology from the University of California, Berkeley. Hers main research interests lie in the dynamic properties and physiological functions of neural circuit activity, the neural circuit basis of brain function and diseases, as well as the structure, function and molecular signaling mechanisms of neuronal synapses.
1.Zhang KM, Shen Y, Jia CH, Wang H, Bi GQ&Lau PM*.A new paradigm of learned cooperation reveals extensive social coordination and specific cortical activation in mice.Mol Brain16,40(2023).
2.Shi DQ, Xu F, Bi GQ&Lau PM*.Conserved Spatiotemporal Dynamics with Millisecond Precision During Reverberatory Activity in a Self-organized Neuronal Network.Neurosci Bull39,808-812 (2023).
3.Xu F#, Shen Y#, Ding LF#, Yang CY#, Tan H, Wang H, Zhu QY, Xu R, Wu FY, Xu C, Li QW, Su P, Zhang LI, Dong HW, Desimone R, Xu FQ, Hu XT,Lau PM*& Bi GQ*. High-throughput whole-brain mapping of rhesus monkey at micron resolution.Nature Biotechnology39,1521-1528 (2021).
4.Shi MY, Ding LF, Guo YH, Cheng YX, Bi GQ* &Lau PM*. Long-range GABAergic projections from the nucleus of the solitary tract.Molecular Brain14, 38(2021).
5.Liu Y-T#, Tao CL#, Zhang XK#, Xia WJ,Shi DQ, Qi L, Xu C, Sun R, Li XW,Lau PM*, Zhou Z H* & Bi GQ*. Mesophasic organization of GABAA receptors in hippocampal inhibitorysynapse.Nature Neuroscience23, 1589–1596 (2020).
She has published more than 30 SCI papers in journals including Nature Biotechnology, Nature Neuroscience, PNAS, and Journal of Neuroscience. Hers main research achievements include:Using photoactivation approaches to demonstrate that local calcium signaling regulates the rapid formation and growth of filopodia in neuronal growth cones;Employing patch-clamp recording and calcium imaging to uncover the synaptic transmission mechanisms underlying reverberatory activity in neural networks;Revealing the neural circuit mechanisms by which stress modulates self-injurious behavior and other stress-related disorders in animal models.