ResearchBy using combined approaches such as classic behavioral pharmacology, electrophysiology and novel neuronal modulation techniques, we try to understand the neural mechanism of drug addiction, anxiety and other neuropsychiatric disorders. The long-term goals of our research are: 1) develop new animal models of these disorders; 2) develop new drugs to prevent the abuse liability of prescribed drugs or new treatment for these disorders.
Biography2019.1- present, Investigator, BCBDI-Shenzhen Institutes of Advanced Technology, CAS.
2017.3-2019.1, Postdoc., Brandeis University.
2013.8-2017.2, Instructor, University of Mississippi Medical Center.
2010.8-2013.8, Research Fellow., Harvard Medical School.
2003.9-2010.3, Ph.D., Kunming Institute of Zoology, CAS.
1999.9-2003.6, B.S., Hebei Normal University.
Selected publications1. Meng Z, Berro LF, Sawyer EK, Ruedi-Betteschen D, Cook JE, Li G, Platt DM, Cook JM, Rowlett JK. Evaluation of the anti-conflict, reinforcing, and sedative effects of YT-III-31, a ligand functionally selective for alpha3 subunit-containing GABAA receptors. Journal of Psychopharmacology, 2019; DOI: 10.1177/0269881119882803
2. Liu C*, Meng Z#, Wiggin TD#, Yu J, Reed M, Guo F, Zhang Y, Rosbash M, Griffith LC*. A Serotonin-modulated circuit controls sleep architecture to regulate cognitive function independent of total sleep in Drosophila. Current Biology, 2019; 29: 3635–3646 (#Equal contribution，*corresponding author)
3.Duke AN#, Meng Z#, Platt DM, Atack JR, Dawson GR, Reynolds DS, Phani Babu Tiruveedhula VVN, Li GG, Stephen MR, Sieghart W, Cook JM, Rowlett JK. Evidence that sedative effects of benzodiazepines involve unexpected GABAA receptor subtypes: quantitative observation studies in Rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics, 2018; 366:145-157 (#Equal contribution)
4.Meng Z, Rowlett JK. Self-administration of progesterone and synthetic neuroactive steroids by male rhesus monkeys. Drug and Alcohol Dependence, 2016; 165:265-9.
5.Meng Z*, Liu C, Yu C, Ma Y*. Transcranial direct current stimulation of the frontal-parietal-temporal area attenuates smoking behavior. Journal of Psychiatric Research, 2014; 54:19-25. (*corresponding author)
6.Meng Z#, Zhou D#, Wang J, Ma Y. Chronic morphine treatment decreases acoustic startle response and prepulse inhibition in rats. Science China Life Sciences, 2010; 53 (11): 1356-1360. (#Equal contribution).
7.Meng Z, Zhang Y, Chen N, Miao Y, Hu X*, Ma Y*. Effects of morphine on pupillary light reflex in monkeys. Zoological Research, 2010; 31 (3): 282-286.
8.Meng Z, Liu C, Hu X*, Ma Y*. Irregular morphine administration affects the retention but not acquisition of conditioned place preference in rats. Brain Research, 2010, 1311: 86-92
9.Meng Z#, Liu C#, Hu X*, Ma Y*. Somatosensory cortices are required for the acquisition of morphine-induced conditioned place preference in rats. PLoS One, 2009, 4(11):e7742 (#Equal contribution).